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VOLUME 2 - NUMBER 3 - 2025

The role of key performance indicators in IVF laboratory

  • Beatrice Maria Barbagallo, Daria Marzanati, Alessandro Bartolacci, Anna Cecchele, Giulia D’Alessandro, Sofia de Girolamo, Stefania Esposito, Arianna Frezza, Luigi Mazzagatti, Luca Pagliardini, Elisa Rabellotti, Lucia De Santis
  • Original Article, 34-39
  • Full text PDF

  • Purpose: The purpose of this study, conducted at the “Centro Scienze della Natalità” of San Raffaele Scientific Institute, is to assess the quality of monthly results through laboratory KPI (Key Performance Indicators) analysis. To achieve this, the Shewhart control chart, is a statistical tool used to monitor data variability over time and detect deviations from the mean.

    Methods: Specific KPIs were selected because they are functional for monitoring and verifying the performance of both the IVF laboratory and the processes preceding oocyte pick-up, such as ovarian stimulation. The selected KPIs: metaphase II oocyte rate (MII rate), immature oocyte rate (GV rate), fertilization rate, the three pronuclei zygote rate (3PN rate) and blastulation rate. Shewhart control charts were used to track variability in these KPIs and detect deviations from the mean, with data collected monthly.

    Results: The analysis of KPIs showed that the IVF laboratory maintained high-quality standards and consistently met its performance objectives. The MII rate, GV rate, fertilization rate, 3PN rate, and blastulation rate were all within acceptable limits, and fluctuations were monitored to identify and address any critical issues. The results indicate that the laboratory is continuously improving its processes, effectively resolving issues, and enhancing its overall performance.

    Conclusions: The use of KPI monitoring through Shewhart control charts is essential for maintaining high-quality standards in IVF laboratories. This study demonstrated that the systematic tracking of KPIs not only supports the identification of areas for improvement but also ensures continuous optimization of laboratory performance and patient care.

  • KEY WORDS: IVF laboratory, performance indicator, KPI, quality control, laboratory performance.